Can Lupron cause permanent menopause? - Balanced Hormone Clinic

Lupron is a medication used to treat conditions like prostate cancer, endometriosis, and precocious puberty. It works by lowering the body's production of certain hormones. When used to treat endometriosis or other gynecological conditions, Lupron puts the body into a temporary menopausal state by suppressing estrogen production. This can relieve symptoms like pelvic pain and heavy menstrual bleeding. However, Lupron rarely causes permanent menopause. Here are some key points about Lupron and menopause risk:

• Lupron causes a temporary pseudo-menopause while a woman is actively taking the medication and for a short time after stopping it. This is an expected side effect of the drug.
• After stopping Lupron, most women will regain normal hormone function and be able to menstruate again. One study found normal cycles resumed within 6 months for 95% of women after Lupron treatment.
• There have been some reports of premature ovarian failure and early menopause associated with Lupron. However, the risk appears to be very low, probably around 1% or less of users.
• Risk factors for permanent menopause with Lupron include:
  • Older age - women over 45 seem to have a higher risk
  • Longer duration of Lupron treatment
  • Existing ovarian damage or dysfunction
  • History of previous chemotherapy
• For most women who take Lupron at younger ages for short periods (up to 6 months), normal hormone function returns and their ovaries can continue working well for years afterwards.

So in summary - yes, permanent menopause is a risk with Lupron treatment. But for generally healthy women receiving short-term treatment, that risk seems to be very small.

What if you're worried about menopause risk with Lupron?

• Discuss the pros and cons with your doctor. They should explain the drug's effects on hormones and menstruation.
• Consider lower dose or shorter treatment options to reduce risk. Many doctors now favor 3-6 months maximum of Lupron instead of longer durations.
• Have your ovarian reserve tested with bloodwork or ultrasound before starting Lupron. This can assess how well your ovaries are working to start with.
• Monitor hormone levels while you are on Lupron to make sure they return to normal ranges afterwards.
• Report any lasting menstrual changes to your doctor promptly. Certain treatments may help restart ovulation.

Are you struggling with hormonal issues or menopause concerns?

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We offer customized programs using bioidentical hormones, nutrition, fitness and lifestyle changes to help women feel their best. Contact us today for a consultation.